Herbs and Herbal Supplements, a Novel Nutritional Approach in Animal Nutrition

Document Type : Review Article


Department of Food Science and Nutrition, Sultan Qaboos University, Al-Koud, Sultanate, Oman


Livestock are an integral part of the agriculture sector and encompass a great impact on the national economy. An eco-friendly alternative to enhance production, prevent and treat disease conditions of animal is a great challenge for animal nutritionists. Keeping farm animals healthy is necessary to obtain healthy animal products. The use of naturally occurring compounds like herbs, herbal preparations and other botanicals are preferred over chemical compounds for enhancement of overall animal health and to satisfy consumer concerns as well. As herbal feed additives may be used drug (finely divided dry medicinal herbal raw materials), herbal extracts or herbal isolate (e.g. essential oil). Herbal drug is a whole or cut up, dry (occasionally raw) part of a plant, algae, fungi or lichen which is used for its medicinal properties. Herbs enhance and add flavors in animal feed and can therefore influence eating patterns, secretion of digestive fluids and total feed intake. The primary site of activity is the digestive tract. Due to the wide variety of active components, different herbs and spices affect digestion processes differently. Herbs, spices and their mixtures are also recognized as anti-inflammatory agents, and also act as antioxidants. Several in-vitro experiments have proved certain plant extract exhibit strong antimicrobial activity against Gram− and Gram+ bacteria. Herbs and their preparation have an affirmative impact on feed intake, growth, meat, milkand egg production. They also have known to enhance the quality and stability of animal products.


Abascal K. and Yarnell E. (2008). Botanical Galactagogues, Mary Ann Liebert, Inc.
Ahmed S. (2010). In-vitro effects of aqueous extract of garlic (Allium sativum) and onion (Allium sepa) on Trichomonas vaginalis. Parasitolog. Unit. J. 3, 45-54.
Ahmed A.A., Bassuony N.I., Awad E.S., Aiad A.M. and Mohamed S.A. (2009). Adding natural juice of vegetables and fruitage to ruminant diets (B) nutrients utilization, microbial safety and immunity, effect of diets supplemented with lemon, onion and garlic juice fed to growing buffalo calves. World J. Agric.Sci. 5 (4), 456-465.
Al Kassie G.A. (2009). Influence of two plant extracts derived from Thyme and Cinnamon onbroiler performance. Pakistan Vet. J. 29, 169-173
Al Kirshi R.A., Alimon A.R., Zulkifli I., Sazili A.O. and Zahari M.W. (2009). The chemical composition and nutritive value of mulberry leaf as a protein source in poultry diets. Pp. 98-102 in Proc. 1st Int. Seminar Anim. Indust., Bogor Agricultural University, Bogor, Indonesia.
Albercht R.M. (1979). Macrophages in the immune response. Pp. 81-91 in Immunologic Tolerance and Macrophage Function. P. Baram, J. Battisto and C. Pierce, (Eds). Elsevier, Amsterdam.
Ali M.S., Saleem M., Ahmad W., Parvez M. and Yamdagni R. (2002). A chlorinated monoterpene ketone, acylated b-sitosterol glycosidesand a flavanone glycoside from Mentha longigolia (Lamiaceae). Phytochemistry. 59, 889-895.
Alimon A.R. (2009). Herbs and herbals in animal nutrition. Pp. 13 in Proc.1st Int. Seminar Anim. Indust. Faculty of Animal Science, Bogor Agricultural University,
Allen P.C., Lydon J. and Danforth H.D. (1997). Effects of components of Artemisia annua on coccidian infections in chickens. Poult. Sci. 76, 1156-1163.
Al-Rofaai A., Rahman W.A., Sulaiman S.F., Yahaya Z.S. (2012). In vitroactivity of neem (Azadirachta indica) and cassava (Manihot esculenta) on three pre-parasitic stages of susceptible and resistant strains of Teladorsagia (Ostertagia) circumcincta. Vet. Parasitol. 3, 188(1-2): 85-92.
Allard J., Kurian R., Aghdassi E., Muggli R. and Royall D. (1997). Lipid peroxidation during n-3 fatty acid and vitamin E supplementation in humans. Lipids. 32, 535-541.
Ando S., Nishida T., IshidaM., Kochi Y., Kami A. and Se S. (2001). Transmission of herb essential oil to milk and change of milk flavor by feeding dried herbs to lactating cows (in Japanese). Nippon Shokuhin Kagaku Kogaku Kaishi. 48,142-145.
Anadon A. (2006). The EU ban of antibiotics as feed additives: alternatives and consumer safety. J.Vet. Pharmacolo. Ther. 29, 41-44.
Anjaria J.V. and Gupta I. (1967). Studies on lactogenic property of Leptadenia reticulata (Jivanti) and leptaden tablets in goats, sheep, cows and buffaloes. Indian Vet. J. 44, 967-974.
Arora V.P. (1989). The effect of Galog on milk production. Pashudhan, 4, 4-5.
Aurousseau B. (2002). Oxygen radicals in Farm animals. Physiological effects and consequences on animal products. INRA Prod. Anim. 15, 67-82.
Bakhiet A. O. and Adam S. E. I. (1995). Therapeutic utility, constituents and toxicity of some medicinal plants: a review. Veter. Human. Toxicol. 37, 255-258.
Baratta M.T., Dorman H.J.D., Deans S.G., Biondi D.M. and Ruberto G. (1998). Chemical composition, antimicrobial and antioxidative activity of laurel, sage, rosemary, oregano and coriander essentials oils. The J. Essent. Oil Res. 10, 618-627.
Barry T.N. and McNabb W.C. (1999). The implications of considered tannins on the nutritive value and temperature forage fed to ruminants. Bri. J. Nut. 81, 263-272.
Benchaar C., Petit H.V., Berthiaume R., Ouellet D.R., Chiquette J. and Chouinard P.Y. (2007). Effects of essential oils on digestion, ruminal fermentation, rumen microbial populations, milk production, and milk composition in dairy cows fed alfalfa silage or corn silage. J. Dairy Sci. 90, 886-897.
Beauchemin K.A. and McGinn S.M. (2006). Methane emissions from beef cattle: Effects of fumaric acid, essential oil, and canola oil. J. Anim. Sci. 84, 1489-1496.
Bhatt N. (2000). Efficacy of Herbal Drugs in Rumen Metabolism, Growth and Milk Production in Crossbred Cattle. G.B. Pant university of Agriculture and Technology, Pantnagar, Uttranchal India.
Bhatt N., Singh M. and Ali A. (2009). Effect of feeding herbal preparations on milk yield and its correlation with rumen parameters in crossbred cows. Int. J. Agric. Biol. 195, 721-726.
Botsoglou N.A., Fletouris D.J., Florou-Paneri P., Christaki E. and Spais A.B. (2003a). Inhibition of lipid oxidation in long-termfrozen stored chicken meat by dietary oregano essential oil and [alpha]-tocopheryl acetate supplementation. Food Res. Int. 36, 207-213.
Botsoglou N.A., Grigoropoulou S.H., Botsoglou E., Govaris A. and Papageorgiou G. (2003b). The effects of dietary oregano essential oil and [alpha]-tocopheryl acetate on lipid oxidation in raw and cooked turkey during refrigerated storage. Meat Sci. 65, 1193–1200.
Bown D. (1997). Encyclopedia of Herbs Andtheir Uses. Dorling Kindersley Publishing, London, UK.
Bravo L. (1998). Polyphenols: chemistry, dietary sources, metabolism, and nutritional significance. Nutr. Rev. 56, 317-333.
Barhane M. and Singh V.P. (2002). Effect of feeding indigenous galactopoietics feed supplements on milk production in crossbred cows. Ind. J. Anim. Sci. 72(7), 609-611.
Bunglavan S.J., Valli C., Ramachandran M. and Balakrishnan, B. (2010). Effect of supplementation of herbal extracts on methanogenesis in ruminants. Lives. Res. Rural Dev. 22(11), 112-123
Burt S. (2004). Essential oils: their antibacterial properties and potential applications in foods – a review. Int. J. Food Microbiol. 94, 223-253.
Butter N.L., Dawson J.M. and Buttery P.J. (1999). Effect of dietary tannins of ruminants. Pp. 51–70 in: Secondary Plant Products. J.C. Caygill and I. Mueller-Harvey, (Eds.). Nottingham, NottinghamUniversity Press.
Busquet M., Calsamiglia S., Ferret A., Carro M.D.and Kamel, C. (2005). Effect of garlic oil and four of its compounds on rumen microbial fermentation. J. Dairy Sci. 88, 4393-4404.
Çabuk M., Bozkurt M., Alçiçek A., Akba Y. and Küçükyýlmaz K. (2006). Effect of a herbal essential oil mixture on growth and internal organ weight of broilers from young and old breeder flocks. South African J. Anim. Sci. 36, 135-141.
Calsamiglia S., Busquet M., Cardozo P.W., Castillejos L. and Ferret A. (2007). Invited review: essential oil as modifiers of rumen microbial fermentation. J. Dairy sci. 90, 2580-2595.
Camara C.C., Nascimento N.R., Macedo-Filho C.L., Almeida F.B. and Fonteles M.C. (2003). Antispasmodic effect of the essential oil of Plectranthus barbatus and some major constituents on the guinea-pig ileum. Planta Med. 69, 1080-1085.
Cardozo P.W., Calsamiglia S., Ferret A. and Kamel C. (2006). Effects of alfalfa extract, anise, capsicum, and a mixture of cinnamaldehyde and eugenol on ruminal fermentation and protein degradation in beef heifers fed a high-concentrate diet. J. Anim. Sci. 84, 2801-2808.
Castillo M., Martín-Orúe S.M., Roca M., Manzanilla E.G., Ba-diola I., Perez J.F. and Gasa J. (2006). The response of gastroin -testinal microbiota to avilamycin, butyrate, and plant extracts in early-weaned pigs. J. Anim. Sci. 84, 2725–2734.
Castillejos L., Calsamiglia S., Ferret A. and Losa R. (2005). Effect of a specific blend of essential oil compounds and the type of diet on rumen microbial fermentation and nutrient flow from a continuous culture system. Anim. Feed Sci. Tech. 119, 29-41.
CastillejosL., Calsamiglia S. and Ferret, A. (2007). Effect of essential oil active compounds on rumen microbial fermentation and nutrient flow in in-vitro system. J Dairy Sci. 89, 2649-2658.
Catoni C., Peters A. and Schaefer H.M. (2008). Life history trade-offs are influenced by the diversity, availability and interactions of dietary antioxidants. Animal Behaviour. 76, 1107-1119.
Celi P. and Raadsma H.W. (2009). The effects of Yerba Mate (Ilex paraguarensis) supplementation on the productive performance of lambs. Pp. 804-805. in Proc. 11th Int. Symp. Rumin. Physiol., Clermont-Ferrand, France.
CeliP. and Raadsma H.W. (2010). The effects of Yerba Mate (Ilex paraguarensis) supplementation on the productive performance of lactating dairy cows. Ani. Pro. Sci. 50, 339-344.
Ćetković G.S., Djilas S.M., Canadanovic-Brunet J.M. and Tumbas V.T. (2004). Antioxidant properties of marigold extracts. Food Res. Int. 37, 643-650.
Chaucheyras F., Fonty G., Bertin G. and Gouet,P. (1995). Effect of Saccharomyces cerevisiae cells on zoospore, germination, growth and cellulolytic activity of the rumen anaerobic        fungus Neocallimastix frontalis MCH3. Curr. Microbiol. 31, 201-205.
Chaudiere J. and Ferrari-Iliou R. (1999). Intracellular antioxidants: from chemical to biochemical mechanisms. Food Chem. Toxicol.. 37, 949-62.
Cheel J., Theoduloz C., Rodriguez J. and Schmeda-Hirschmann G. (2005). Free radical scavengers and antioxidants from Lemongrass (Cymbopogon citratus (DC.) Stapf.). J. Agric. Food Chem. 53, 2511-2517.
Chen Y.G., Sun Y.G., Huang D.P. and Wang D.L. (2009). Effect of Chinese medicine herbal synbiotics on production capability and apparent digestibil ity of feed on weaned piglets. J. Domest. Anim. Ecolo. 30, 39-40.
Chesson A., StewartC.S. and Wallace R.J. (1982). Influence of plant phenolic acids on growth and cellulolytic activity of rumen bacteria. Appl. Environ. Microbiol. 44, 597-603.
Cole N.A. and Todd R.W. (2008). Opportunities to enhance performance and efficiency through nutrient synchrony in concentrate–fed ruminants. J. Anim. Sci. 86, 318-333.
Cowan M.M. (1999). Plant products as antimicrobial agents. Clin. Microbiol. Rev. 12, 564-582.
Craig W.J. (1999). Health-promoting properties of common herbs. Am. J. Clin. Nut. 70, 491-499.
Craig W.J. (2001). Herbal remedies that promote health and prevent disease. Pp. 179-204. in: Vegetables, Fruits, and Herbs in Health Promotion. R.R. Watson, (Ed.). Florida, CRC Press, Boca Raton.
Davis S.R. (2005). An overview of the antifungal properties of allicin and its breakdown   products-the possibility of a safe and effective antifungal prophylactic. Mycoses. 48(2), 95-100.
Deckert V., DesrumauxC., Athias A., Duverneuil L., Palleau V., Gambert P., Masson D. and Lagrost L. (2002). Prevention of LDL-tocopherol consumption, cholesterol oxidation, and vascular endothelium dysfunction by polyphenolic compounds from red wine.Atherosclerosis. 165, 41-50.
Delgado-Vargas F. (1997). Pigments of the flower cempxuchitl (Tagetes erecta). Physiochemical characterization, processing, and pigmenting efficiency. Ph.D. Thesis. National Polytechnic Institute, Mexico City, Mexico.
Demir E., Sarica S., Ozcan M.A. and Swemez M. (2003). The use of natural feed additives as alternatives for an antibiotic growth promoter in broiler diets. Br. Poult. Sci. 44, 44-45.
De Rosa M., Gambacorta A. and Gliozzi. (1986). Structure, biosynthesis and physic-chemical properties or archaebacterial lipids. Microb. Rev. 50, 70-80.
Dikshit A. and Husain A. (1984). Antifungal action of some essential oils against animal pathogens. Fitoterapia. 7, 171-176.
Dorman H.J.D. and Deans S.G. (2000). Antimicrobial agents from plants: antibacterial activity of plant volatile oils. J. Appl. Microbiol. 88: 308-316.
Dorman H.J.D., Kosar M., Kahlos K., Holm Y. and Hiltunen R. (2003). Antioxidant properties and composition of aqueous extractsfrom Mentha species, hybrids, varieties, and cultivars. J. Agric. Food Che. 51, 4563-4569.
Duthie H.L. (1981). The effect of peppermint oil on colonic motility in man. Surg. Res. Soc. Abstr. 68, 820-825.
El-Astal Z. (2004). The inhibitory action of aqueous garlic extract on the growth of certain pathogenic bacteria. Eur. Food Res. Tech. 218(5), 460-464.
Erasmus L.J., Robinson P.H., Ahmadi A., Hinders R. and Garrett J.E. (2005). Influence of prepartum and postpartum  supplementation of  a yeast culture and monensin, or both on ruminal fermentation and performsnce of multiparous cows. Ani Feed Sci Tech. 145, 219-239.
Esparza-Borges H. and Ortiz-Márquez A. (1996). Therapeutic efficacy of plant extracts in the treatment of bovine endometritis. Acta Horticulturae (ISHS), 426, 39-46.
Evans J.D. and Martin S.A. (2000). Effects of thymol on ruminal microorganisms. Curr. Microbiol. 41, 336-340.
Fasseas M.K., Mountzouris K.C., Tarantilis P.A., Polissiou M. and Zervas G. (2008). Antioxidant activity in meat treated withoregano and sage essential oils. Food Che. 106, 1188-1194.
Fang R.J., Tang S. X. and Li T.J. (2000). Effects of Chinese herbal medicine compound additives on growth and substance metabolism in broiler. China Feed. 7, 7-11.
Farag R.S., Daw Z.Y. and Abo-Raya S.H. (1989b). Influence of some essential oils on Aspergillus parasiticus growth and aflatoxins production in a synthetic medium, J. food Sci. 54, 74-67.
Favier A. (1997). Oxidative stress: value of its demonstration in medical biology and problems posed by the choice of a marker. Ann. Biol. Clin. 55, 9-16.
Feix S., Faixová Z., Plachá1I. and Koppel J. (2009). Effect of Cinnamomum zeylanicum Essential Oil on Antioxidative Status in Broiler Chickens. Acta Vet. Brno. 78, 411-417.
Florou-Paneri P., Christaki E., Giannenas I., Papazahariadou M., Botsoglou N.A., Spais A.B. (2004). Effect of dietary olympus tea (Sideritis scardica) supplementation on performance of chickens challenged with Eimeria tenella. J. Anim. Feed Sci. 13, 301-311.
Fuhrmann H. and Sallmann H.P. (1999). Amount and type of unsaturated aldehydes in chicken plasma and tissues depend more on dietary lipids than on vitamin E status. Lipid. 34, 253-254.
Gabay M.P. (2002). Galactagogues: medication that induce lactation. J. Hum. Lac. 18, 274-279.
Gebert S., Stahel F., Messikommer R. and Wenk C. (1999). Rhubarb als alternative zu antimikrobiellen lesitungsförderern (AML) im ferkel- und broiler futter. Pp. 165-166 in: Beitrag derTierernaehrung zur Besonderheit der CH-Produkte. Eds. Sutter, F., Wenk, C., Kreuzer, M. and Hrsg., Schriftenreihe aus dem Institut fuer Nutztierwissenshaften, Ernaehrung-Produkte-Umwelt, ETH Zürich.
Ghalyanchi Langeroudi A., Kiaei S.M.M., Modirsanei M., Mansour B. and Shojaie Estabragh. (2008). Comparison of chemical and biological growth promoter with two herbal natural feed additives on broiler chick performance. J. Anim. Vet. Adv. 5, 570-574.
Ghosh S., Mehta R.M., Sirohi S.K. and Roy B. (2010). The effect of dietary garlic supplementation on body weight gain,feed intake, feed conversion efficiency, faecal score, faecal coliform count and feeding cost in crossbred dairy calves. Trop. Anim. Health  Prod. 42, 961-968.
Giannenas I.A., Florou-Paneri P., Botsoglou N.A., Christaki E. and Spais A.B. (2005). Effect of supplementing feed with oregano and/or tocopheryl acetate on growth of broiler chickens and oxidative stability of meat. J. Anim. Feed Sci. 14, 521-535.
Gill C. (2000). Botanical feed additives. Feed. Int. 21, 14-17.
Grzanna R., Lindmark L. and Frondoza C.G. (2005). Gingeran herbal medicinal product with broad anti-inflammatory actions. J. Med. Food. 8(2), 125-132.
Greathead H. (2003). Plants and plants extracts for improving animal productivity. Proc. Nutr. Soci. 62: 279-290.
Guo A.W., Zhou J.L., Zhu J., Deng T.Q., Huang F. and Liu B. (2008). Effects of Chinese herbals medicine compound substi tuting antibiotics on performance and substance metabolism in broilers. Acta Agric. Univ. Jiangxiensis. 36, 978-980.
Halliwell B., Aeschbach R., Löliger J. and Aruoma O.I. (1995). The characterization of antioxidants. Food Chem. Toxicol. 33, 601–617.
Harnafi H. and Amrani S. (2007). Flaveniods as potent phytochemicals in cardiovascular diseases prevention. Pharmac. Rev. 1, 193-202.
Harris E.D. (1992). Regulation of antioxidant enzymes. Faseb J. 6, 2675-2683.
Hart K.J., Girdwood S.E., Taylor S., Yanez-Ruiz D.R. and Newbold C.J. (2006).Effect of allicin on fermentation and microbial populations in the rumen simulating fermentor Rusitec. Reprod. Nutr. Develop. 46, 97-115.
Hernandez F., Madrid J., Garcia V., Orengo J. and Megias M.D. (2004). Influence of tow plant extracts on broiler performance, digestibility, and digestive organ size. Poult. Sci. 83, 169-174.
Hess H.D., Monsalve L.M., Lascano C.E., Carulla J.E., Diaz T.E., Kreuzer M. (2003a). Supplementation of a tropical grass diet with forage legumes and Sapindus saponaria fruits: effects on in vitro ruminal nitrogen turnover and methanogenesis. Australian J. Agric. Res. 54, 703-713.
Hills J.M. and Aaronson P.I. (1991). The mechanism of action of peppermint oil on gastrointestinal smooth muscle. An analysis using patch clamp electrophysiology and isolated tissue pharmacology in rabbit and guinea pig. Gastroenterology. 101, 55-65.
Hosoda K., Kuramoto K., Eruden B., Nishida T. and Shioya S. (2006). The effects of three herbs as feed supplements on blood metabolites, hormones, antioxidant activity, igg concentration, and ruminal fermentation in Holstein steers. Asian-australs J. Anim. Sci. 19, 35-41.
Hosoda K., Nishida T., Park W.Y. and Eruden B. (2005). Influence of Mentha×piperita L. (Peppermint) supplementation on nutrient digestibility and energy metabolism in lactating dairy cows. Asian-australs J. Anim. Sci. 18, 1721-1726.
Hristov A.N., Ivan M., Neill L. and Mcallister T.A. (2003) Evaluation of several potential bioactive agents for reducing protozoal activity in vitro. Anim. Feed Sci. Technol. 105, 163-184.
Imai H., Osawa K., Yasuda H., HamashimaH., Arai T. and Sasatsu M.( 2001). Inhibition by the essential oils of peppermint and spearmint of the growth of pathogenic bacteria. Microbios 106, 31-39.
Jacobsen C., Let M.B., Nielsen N.S. and Meyer A.S. (2008). Antioxidant strategies for preventing oxidative flavour deterioration of foods enriched with n-3 polyunsaturated lipids: a comparative evaluation. Trend. Food Sci. Technol. 19, 76-93.
Jackson P., Rook J.A.F. and Towas K.C. (1971). Influence of the physical form of barley grain and barley straw diet on nitrogen metabolism in sheep. J. Dairy Res. 38, 33-42.
Jakhar G. (1995). Effect of Ruchamax feeding on growth promotion in piglets. Int. Vet. Med. J.19(2), 158-160.
Jamroz D., Orda J., Kamel C., Williczkiewicz A., Wertelecki T. and Skorupin’Ska J.( 2003). The influence of phytogenic extract on performance, nutrients digestibility, carcass characteristic and gut microbial status in broiler chickens. J. Anim. Feed Sci. 12(3),583-596.
Jang A., Liu X.D., Shin M.H., Lee B.D., Lee S.K., Lee J.H. and Jo C. ( 2009). Antioxidative potential of raw breast meat from broiler chicks fed a dietary medicinal herb extract mix. Poul. Sci. 87, 2382-2389.
Janssen A.M. (1989). Antimicrobial Activities of Essential Oils. A Pharmacognostical Study Dissertation, Rijksuniversiteit Leiden.
Janz J.A.M., Morel P.C.H., Wilkinson B.H.P. and Purchas R.W. (2007). Preliminary investigation of the effects of low-leveldietary inclusion of fragrant essential oils and oleoresins on pig performance and pork quality. Meat Sci. 75, 350-355.
Jugl-Chizzola M., Ungerhofer E., Gabler C., Hagmüller W.,Chizzola R., Zitterl-Eglseer K. and Franz C.( 2006). Testing of the palatability of Thymus vulgaris L. and Origanum vulgare L. as flavouring feed addititve for weaner pigs on the basis of a choice experiment. Berliner und Münchener Tierärztliche Wochenschrift. 119, 238–243.
Kamal-Eldin A. and Yanishlieva N. (2002). n−3 fatty acids for human nutrition: stability considerations. Eur. J. Lipid Sci. Technol. 104, 825-836.
Kamra D.N., Singh R., Agarwal N. and Pathak N.N. (2000). Soapnut (Reetha) as natural defaunating agent its effect on rumen fermentation and in sacco degradability of jowar hay in buffaloes. Buffalo J. 16, 99-104.
Kanatt S.R., Chander R. and Sharma A. (2007). Antioxidant potential of mint (Mentha spicata L.) in radiation-processed lamb meat. Food Chem. 100, 451-458.
Kawakami Y., Tsurugasaki W., Yoshida Y., Igarashi Y., Nakamura S. and Osada K.( 2004). Regulative actions of dietary soy isoflavone on biological antioxidative system and lipid metabolism in rats. J. Agric. Food Chem. 52, 1764-1768.
Kende M. (1982). Role of macrophages in the expression of immune responses. J. Am. Vet. Med. Ass. 181, 1037-1042.
Kolte A.Y., Waghmare S.P., Mode S.G. and Handa A. ( 2008). Efficacy of indigenous herbal preparation on altered milk pH, somatic cell count and electrolyte profile in subclinical mastitis in cows. Vet. World. 1(8), 239-240.
Kondo M., Nakano M., Kaneko A., Agata H., Kita K. and Yokota H. (2004). Ensiled green tea waste as partial replacement for soybean meal and alfalfa hay in lactating cows.Asian-Australs J. Anim. Sci. 17, 960-966.
Kudke R.J., Kalaskar S.R. and Nimbalkar R.V. (1999). Neem leaves as feed supplement for livestock. Paushudhn. 14, 12-14.
Kumar B. and Shah K.K. (1995). Effect of feeding Livol on growth and wool production of angora rabbits. Pashudhan. 10 (9), 4-8.
Kumari R. and Akbar M.A. (2006). Clinical efficacy of some herbal drugs during indigestion in buffaloes. Buffalo Bull. 25, 3-6.
Kuzmicky D.D., KohlerG.O., Livingston A.L., Knowles R.E. and Nelson J.W. (1969). Broiler pigmentation potency of neoxanthin and violaxanthin relative to lutein. Poult. Sci. 49, 326-330.
Kyung K.H., KimM.H., Park M.S. and KimY.S. (2002). Allinase independent inhibition of Staphylococcus aureus B33 by heated garlic. J. Food Sci. 67(2), 780-785.
Lan Y.L., Li F., Wang H.T. and Xu Z.X. (2000). Fattening results of beef cattle by traditional Chinese medicine. J. Yellow Cattle Sci. 26, 25-26.
Lawrence R.A. and Lawrence R.M. (1999). Breastfeeding: A Guide for Medical Profession. St. Louise, Mosby.
Lee K.W., Evert H. and Beynen A.C. ( 2004). Essential oils in broiler nutrition. Int. J. Poult. Sci.3, 738-752.
Leuschner R.G.K. and Zamparini J. (2002). Effects of spices on growth and survival of Escherichia coli O157 and Salmonella enterica serovar Enteritidis in broth model systems and mayonnaise. Food Contol. 13, 399-404.
Lila Z.A., Mohammed N., Kanda S., Kamada T. and Itabashi H. (2003). Effect of sarsaponin on ruminal fermentation with particular reference to methane production in vitro. J. Dairy Sci. 86, 3330-3336.
Lila Z.A., Mohammed N., Yusni T, Kurokawa Y, Kanda S. and Itabashi H. (2004). Effect of a twin strains of Saccharomyces cervisiae live cells on mixed ruminal microorganism fermentation in vitro. J. Anim. Sci. 82, 1847-1854.
Lippens M., Huyghebaert G. and Cerchiari E. (2005). Effect of the use of coated plant extracts and organic acids as alternatives for antimicrobial growth promoters on the performance of broiler chickens. Eur. Poult. Sci. 6, 48-56.
Lopez-Bote C.J., Gray J.I., Gomaa E.A. and Flegal C.J. (1998). Effect of dietary administration of oil extracts from rosemary and sage on lipid oxidation in broiler meat. Br. Poult. Sci. 39, 235-240.
Lykkesfeldt J. and Svendsen O. (2007). Oxidants and antioxidants in disease: oxidative stress in animals. Vet. J. 173, 502-511.
Ma D.Y., Shan A.S. and Li Q.D. (2004). Effects of Chinese medical herbs on chickens growth and immunization. Acta Zoonut. Sini. 16, 36-40.
Madsen H.L. and Bertelsen G. (1995). Spices as antioxidants. Trend. Food Sci. Technol. 6, 271-277.
Madeira S.V.F., Matos F.J.A., Leal-Cardoso J.H. and Criddle D.N. (2002). Relaxant effects of the essential oil of Ocimum gratissimum on isolated ileum of the guinea pig. J. Ethnopharmacol. 81, 1-4.
Mahantra, S.K., Kundu S.S. and Karnani L.K. (2003). Performance of lactating Murrah buffaloes fed a herbal preparation. Indian Buffalo. 1(20), 61-64.
Main R.G., Minton J.E., Dritz S.S., Tokach M.D., Goodband R.D. and Nelssen J.L. (2001). Evaluating cloves as a potential substitute for antimicrobials in nursery pig diets. Kansas Agric. Exp. Sta. Prog. Rep. 880, 32-34.
Makkar H.P.S., Francis G. and Becker K. (2007). Bioactivity of phytochemicals in some lesser-known plants and their effects and potential applications in livestock and aquaculture production systems. Animal. 1, 1371-1391.
Makkar H.P.S., Sen S. Blummel M. and Becker K. (1998). Effects of fractions containing saponins from Yucca schidigera, Quillaja saponaria and Acacia auriculoformis on rumen fermentation. J. Agric. Food Chem. 46, 4324-4328.
Manach C., Scalbert A., Morand C., Re´me´zy C. and Jimenez L. (2004). Polyphenols: food sources and bioavailability. Am. J. Clin. Nutr. 79, 727-747.
Manjunatha H. and Srinivasan K. (2006). Protective effect of dietary curcumin and capsaicin on induced oxidation of low-density lipoprotein, iron-induced hepatotoxicity and carrageenan-induced inflammation in experimental rats. FEBS J. 273, 4528-4537.
Manzanilla E.G., Perez J.F., Martin M., Kamel C., Baucells F. and Gasa J. (2004). Effect of plant extracts and formic acid on the intestinal equilibrium of early-weaned pigs. J. Ani. Sci. 82, 3210–3218.
Marinova E.M. and Yanishlieva N.V. (1997). Antioxidative activity ofextracts from selected species of the family Lamiaceae in sunflower oil. Food Che. 58, 245-248.
Martin G.B. and Kadokawa H. (2006). Clean, green and ethical" animal production. case study: reproductive efficiency in small ruminants. J. Reprod. Develop. 52, 145-152.
McDonald P., Edwards R.A. and Greenhalgh J.F.D. (1990). Animal Nutrition, Reprinted English Language Book Society/Longman.
McDonald P., Edwards R.A., Greenhalgh J.F.D. and Morgan C.A. (2002). Animal Nutrition. Pearson Education Limited, Essex, England.
McIntosh F.M., Williams P., Losa R., Wallace R.J., Beever D.A. and Newbold C.J. (2003). Effects of essential oils on ruminal microorganisms and their protein metabolism. Appl. Environ. Microbiol. 69, 5011-5014.
Meichin Y., HuiChing C. and ShyhMing Tsao. (2002). Inhibitory effects of aqueous garlic extract, garlic oil and four diallyl sulphides against four enteric pathogens. J. Food Drug. Anal. 10(2), 120-126.
Miller J.K. and Brzezinska-Slebodzinska E. (1993). Oxidative stress, antioxidants and animal function. J. Dairy Sci. 76, 2812-2823.
Miller N.J., Rice-Evans C., Davies M.J., Gopinathan V. and Milner A. (1993). A novel method for measuring antioxidant capacity and its application to monitoring the antioxidant status in premature neonates. Clin. Sci. 84, 407-412.
Mishra, A., Niranjan, A., Tiwari S.K., Prakash D., Pushpangadan S. (2008). Nutraceutical composition of Asparagus racemosus (Shatavari) grown on partially reclaimed sodic soil. J. Med. Aroma. Plant Sci. 27, 240-248.
Montes-Belmont R. and Carvajal M. (1998). Control of Aspergillus flavus in maize with plant essential oils and their components. J. Food Prot. 61, 616-619.
Muhl A. and Liebert F. (2007). Growth and parameters of microflora in intestinal and faecal samples of piglets due to application of a phytogenic feed additive. J. Anim. Physiol. Anim. Nutr. 91, 411-418.
Mukai K., Sawada K., Kohno Y. and Terao J. (1993). Kinetic study of the prooxidant effect of tocopherol. Hydrogen abstraction from lipid hydroperoxides by tocopheroxyls in solution. Lipids. 28, 747-752.
Nakamura T., Klopfenstein T.J., Gibb D.J. and Britton R.A. (1994). Growth efficiency and digestibility of heated protein fed to growing ruminants. J. Anim. Sci. 72, 774-782.
Namkung H., Li M., Gong J., Yu H., Cottrill M. and de Lange C.F.M. (2004). Impact of feeding blends of organic acids and herbal extracts on growth performance, gut microbiota and digestive function in newly weaned pigs. Can. J. Anim. Sci. 84, 697-704
Neville M.C., Morton J. and Unemura S. (2001). Lactogenesis: transition from pregnancy to lactation. Ped. Clin. North Am. 48, 45-52.
Newman D.J., Cragg G.M. and Snader K.M. (2000). The influence of natural products upon drug discovery. Natio. Prod. Rep. 17, 215-234.
Newbold C.J., McIntosh F.M., Williams P., Losa R. and Wallace R.J. (2004). Effects of a specific blend of essential oils on rumen fermentation. Anim. Feed Sci. Technol. 114, 105-112.
Niki E., Yoshida Y., Saito Y. and Noguchi N. ( 2005). Lipid peroxidation: mechanisms, inhibition, and biological effects. Biochem. Biophys. Res. Commun. 338, 668-676.
Nikolic V.D., Stankovic M.Z., Nikolic L.B., Cvetkovic  D.M. and Skala, D.U. (2004). Antimicrobial effect of raw garlic (Allium sativum L.) extracts, garlic  powder and oil and commercial antibiotics on pathogen. Hemijska Industrija. 58(3), 109-113.
Ocak N., Erener F., Burak A.K., Sungu M., Altop A. and Ozmen A. ( 2008). Performance of broilers fed diets supplemented with Dry Peppermint (Mentha piperitaL.) or Thyme (Thymus vulgarisL.) leaves as growth promoter source. Czech. J. Anim. Sci. 53(4), 169-175.
Oldham J.D. (1981). Amino acid requirement of lactation in high yielding dairy cows. Pp. 33-65 in:Recent Advances in Animal Nutrition. W. Harisingh, (Ed.), Butterworth, London.
Papageorgiou G., Botsoglou N., Govaris A., Giannenas I., Iliadis S. and Botsoglou E. (2000). Effect of dietary oregano oil and &-tocopheryl acetate supplementation on iron-induced     lipid oxidation of turkey breast, thigh, liver and heart tissues. J. Anim. Physiol. Anim. Nutr. 87, 324-335.
Park I.K. and Shin S.C. (2005). Fumigant activity of plant essential oils and components from garlic (Allium sativum) and clove bud (Eugenia caryophyllata) oils against the Japanese termite (Reticulitermes speratus Kolbe). J. Agric. Food Chem. 53, 4388-4392.
Pasqua R.D., Hoskins N., Betts G. and Mauriello G. (2006). Changes in membrane fatty acids composition of microbial cells induced by addiction of thymol, carvacrol, limonene, cinnamaldehyde, and eugenol in the growing media. J. Agric. Food Chem. 54, 2745-2749.
Patra A.K., Kamra D.N. and Agarwal N. (2006).Effect of plant extract on in vitro methanogenesis, enzyme activities and fermentation of feed in rumen liquor of buffalo, Anim. Feed Sci. Technol. 128, 276-291.
Pattnaik S., Subramanyam V.R. and Kole C. (1996). Antibacterial and antifungal activity of ten essential oils in vitro. Microbio. 86, 237-246.
Pen B., Sar C., Mwenya B., Kuwaki M., Morikawa R. and Takahashi J. ( 2006) Effects of Yucca schidigera and Quillaja saponaria extracts on in vitro ruminal fermentation and methane    emission. Anim. Feed Sci. Technol. 129, 175-186.
Phalphale P.B., BhaleaoD.P. and Jagdish S. (1997). Clinical efficacy of Ruchamax in the treatment of anorexia in goats. Int. Vet. J.74, 598-600.
Patel, A.B. and Kanitkar U.K. (1969). Asparagus racemosus willd. Form bordi, as a galactagogue in buffaloes. Indian Vet. J. 46, 718-721.
Patel K. and Srinivasan K. (2001). Studies on the influence of dietary spices on food transit time in experimental rats. Nutr. Res. 21, 1309-1314.
Pradhan N.R. and Biswas U. (1994). Studies on the efficacy of Ruchamax against indigestion in cattle. Int. Vet. Med. J. 18 (4), 268-272.
Preciado A.T., Orozco Hernandez J.R. and Contreras Carraza A., Carranza de la Mora, V., Rocha Chavez G. ( 2011). Use of an herbal galectogogue on milk quality and yield. Asian J. Anim. Vet. Advan. 6 (3), 297-300.
PrestlØkken E. (1999a). In-situ ruminal degradation and intestinal digestibility of dry matter and protein in expanded feedstuffs. Anim. Feed Sci. Technol. 77, 1-23.
PrestlØkken E. (1999b). Ruminal degradability and intestinal digestibility of protein and amino acids in barley and oats expander-treated at various intensities. Anim. Feed Sci. Technol. 82, 157-175.
Quackenbush F.W., Kvakovszky S., Hoover T. and Rogler J.C. (1965). Deposition of individual carotenoids in avian skin. J. AOAC. 48, 1241-1244.
Qureshi M.I. (1999). Efficiency of Lectovet as a galactagogue in dairy cattle. Indian Vet. Med. J. 23, 134-138.
Ragland D., Schneider J., Stevenson D., Hill M.A. and Bakker M. (2007). Oregano oil as an alternative to antimicrobials in nursery diets. J. Swine Health Prod. 15, 346-351.
Rahimi S., Teymouri Zadeh Z., Karimi Torshizi M.A., Omidbaigi R. and Rokni H. (2011).Effect of the three herbal extracts on growth performance, immune system, blood factors and intestinal selected bacterial population in broiler chickens. J. Agric. Sci. Tech. 13, 527-539.
Ramesh P.T., Mitra S.K., Suryanarayan T. and Sachan A. (2000). Evaluation of Galactacin a herbal galactagogue preparation in dairy cows. The Veterinarians. 24, 1-3.
Reite M. and Brandt W. (1985). Relaxant effects on tracheal and ileal smooth muscles of the guinea pig. Arzneimittel forschung. 35, 408-414.
Rohilla P.P. and Bujarbaruah K.M. (1997). Effect of minovit- forte and ruchamax feeding on growth of pigs. Int. Vet. Med. J. 21(1), 238-242.
Rollo C.D. (2002). Growth negatively impacts the life span of mammals. Evol. Develop. 4, 55-61.
Rosen G.D. (1996).Feed additives nomenclature. World’s Poult. Sci. J. 52, 53-56.
Rossi F., Luccia A.D., Vincenti D. and coconcelli P.S. (2004). Effect of peptide fractions from Saccharomycescervisiae culture on growth and metabolism of the ruminal bacteria Megnasphaera elsdenii. Anim. Res. 53, 177-185.
Rossi J. (1995). Additives for animal nutrition and technique for their preparation. European Patent EP 0646321 B1.
Runjaić-Antić D., Pavkov S. and Lević J. (2010). Herbs in a sustainable animal nutrition.Biotech. Anim. Husbandry. 26(3-4), 203-214.
Ryan J.P., Quinn T. and Leek B.L. (1997). Comparison of effects of Yucca schidigera plant extract on ruminal ammonia concentrations (De-Odorize) and saccharomyces cervisiae yeast culture (Yea-Sacc1026) on pH, short chain fatty acids (SCFA) and anmmonium, during fermentation of hay by sheep’s ruminal fluid in vitro. J. Dairy Sci. 81, 3222–323.
Salah N., Miller N., Paganga G.and Tijburg L. (1995). Polyphenolic flavanols as scavengers of aqueous phase radicals and as chain-breaking antioxidants. Arch. Biochem. Biophys. 322, 339-346.
Sardar P., Kewalramani N. and Kaur H. (1997). Influence of livol supplementation on rumen fermentation. Int. J. Anim. Nutr. 14, 189-192.
Saxena M.J. (2008). Herbs a safe and scientific approach. Int. Poult. Prod. 16, 11-13.
Schaefer D.M., DavisC.L. and Bryant M.P. (1980). Ammonia saturation constants for predominant species of bacteria. J. Dairy Sci. 63, 1248-1251.
Scislowski V., Bauchart D., Gruffat D., Laplaud P.M. and Durand D. ( 2005). Effect of dietary n-6 or n-3 polyunsaturated fatty acids protected or not against ruminal hydrogenation on plasma lipids and their susceptibility to peroxidation in fattening steers.J. Anim. Sci. 83, 2162-2174.
Sharma R.K., Maini S. and Ravikanth K. (2008). Beneficial effects of superliv ds and xlivpro on growth promotion and carcass quality traits in broilers. Vet. World. 1(12), 363-365.
Singh N., Akbar M.A., Kumari R. and Khanna B.M. (1996). Effect of some treatment on ruminal environment in milk anorexia. production in clinical cases of digestion in buffaloes. Ind. Vet. Med. J. 20, 115-118.
Singh N., Kumari R., Yadav R.S., Akbar M.A. and Sengupta B.P. (1991). .Effect of some commonly used galactagogue on milk production and biogenic amines in buffaloes.Indian Vet. Med. J. 15, 20-24.
Singhal S.P. (1995). Study on the effect of feeding Payapro on milk yield in lactating cows.Dairy Guide. 1, 45-47.
Sirri F., Iaffaldano N., Minelli G., Meluzzi, A., Rosato M.P. and Franchini A.  (2007). Comparative pigmentation efficiency of high dietary levels of apo-ester and marigold extract on quality traits of whole liquid egg of two strains of laying hens. J. Appl. Poult. Res. 16, 429-437.
Sliwinski B.J., Soliva C.R., Machmuller A. and Kreuzer M. (2002).Efficacy of plant extracts rich in secondary constituents to modify rumen fermentation. Anim. Feed Sci. Tech. 101, 101-114.
Small L.D., Bailey J.H. and Cavallito C.J. (1947). Alkyl thiosulfinates. J. Am.Che. Soci. 69, 1710-1713.
Somkuwar A.P., Khadtare C.M., Pawar S.D. and Gatne M.M. (2005). Influence of shatavari feeding on milk production in buffaloes. Pashudhan. 31(2), 3-7.
Srinivasan K. (2005). Spices as influencers of body metabolism: An overview of three decades of research. Food Res. Int. 38, 77-86.
Sulabo R.C., Jacela J.Y., DeRouchey J.M., Tokach M.D., Neher F., Goodband R.D., Dritz, S.S. and Nelssen J.L. (2007). Effects of phytobiotics (BIOMIN® P.E.P.) on nursery pig performance. Kansas Agric. Exp. Sta. Prog. Rep. 985, 94-98
Suresh D. and Srinivasan K. (2007). Studies on the in vitro absorption of spice principles curcumin, capsaicin and piperine in rat intestines. Food Chem. Toxico. 45, 1437-1442.
Tanwar P.S., Rathore S.S, Kumar Y. (2008). Effect of shatavari (Asparagus recemosus) on milk production in dairy animals. Indian. J. Anim. Res. 42(3), 232-233.
Tassoul M.D. and Shaver R.D. (2009). Effect of a mixture of sup plemental dietary plant essential oils on performance of periparturient and early lactation dairy cows. J. Dairy Sci. 92, 1734-1740.
Thalib A., Widiawatii Y., Hamid H., Suherman D. and Sabrani M. (1996). The effects of saponin from Sapindus rarak on ruminal flora and fermentation characteristics in vitro. J. Ilmu. Ternak dan Vert. 2, 17-20.
Tollba A.A.H. and Hassan M.S.H. (2003). Using some natural additives to improve physiological and productive performance of broiler chicks under high temperature conditions, black cumin (Nigella sativa) or garlic (Allium sativum). Poult. Sci. 23, 327-340.
Traber M.G., Ramakrishnan R. and Kayden H.J. (1994). Human plasma Vitamin E kinetics demonstrates rapid recycling of plasma RRR tocopherol. Proc. Natl. Acad. Sci. 91, 10005-10008.
Turner J.L., Dritz S.S., Higgins J.J. and Minton J.E. (2002). Effects of Ascophyllum nodosum extract on growth performance an immune function of young pigs challenged with Salmonella typhimurium. J. Anim. Sci. 80, 1947-1953.
Unal A. and Kocabagll N. (2014). Effect of different dosages of oregano oil on performance and some blood parameters in lambs. Ankara Üniv. Vet. Fak Derg. 61, 199-204.
Valero M. and Salmeron M.C. (2003). Antibacterial activity of 11 essential oils against Bacillus cereus in tyndallized carrot broth. Int. J. Food Microbiol. 85, 73-81.
Van Furt R. (1982). Current view on the mononuclear phagocyte system. Immunobiology. 161, 178-185.
Viana G.S.B., Vale T.G., Pinho R.S.N. and Matos F.J.A. (2000). Antinociceptive effect of the essential oil from Cymbopogon citratus in mice. J. Ethnopharmacol. 70, 323-327.
Wallace R.J., Arthaud L. and Newbold C.J. (1994). Influence of Yucca shidigera extract on ruminal ammonia concentrations and ruminal microorganisms. Appl. Enviro. Microbiol. 60, 1762-1767.
Wang J.H. and Wang J.Q. (2007). Study of effect of Chinese herbal medicine additive on fattening. China Cattle Sci. 33, 51-52.
Wang H.F., Yang W.R., Wang Y.X., Yang Z. B.and Cui Y.H. (2011). The study on the effects of Chinese herbal mixtures on growth, activity of post-ruminal digestive enzymes and serum antioxidant status of beef cattle. Agric. Sci. China. 10(3), 448-455.
Weisbjerg M.R., Hvelplund T., Hellberg S., Olsson S. and Sanne S. (1996). Effective rumen degradability and intestinal digestibility of individual amino acids in different concentrates determined in situ. Anim. Feed Sci. Tech. 62, 179-188.
Wenk C. (2003). Herbs and botanicals as feed additives in monogastric animals. Asian-australs J. Anim. Sci. 16(2), 282-289.
Wheelar G.E. (1997). Evaluation of Livol as a feed ingredient for optimizing liver function and growth in veal calves. Pashudhan. 12(2), 4-8.
Windisch W.M., Schedle K., Plitzner C. and Kroismayr A. (2008). Use of phytogenic products as feed additives for swine and poultry. J. Anim. Sci. 86, 140-148.
Wood J.D., Richardson R.I., Nute G.R., Fisher A.V., Campo M.M., Kasapidou E., Sheard P.R. and Enser M. (2004). Ef-fects of fatty acids on meat quality: a review. Meat Sci. 66, 21-32.
Woodward S.L., Waghorn G.C., Ulyatt M. J. and Lassey K.R. (2001). Early indication that feeding lotus will reduce methane emission from ruminants. Pp. 23-26 in Proc. 61st Conf. New Zealand Soci. Anim. Produc., Lincolin University, New Zealand.
Yamahara J., Kobayashi M., Saiki Y., Sawada T. and Fujimura H. (1983). Biologically active principles of crude drugs. Pharmacological evaluation of cholagogue substances in clove and its properties. J. Pharmacobiodyn. 6, 81-286.
Yoon I.K. and Stern M.D. (1996). Effect of Saccharomyces cervisiae and Aspergillus oryzae cultures on nominal fermentation in dairy cows. J. Dairy Sci. 79, 411-417.
Youn H.J. and Noh J.W. (2001). Screening of the anticoccidial effects of herb extracts against Eimeriatenella. Vet. Parasitol. 96, 257-263.
Young J.F., Stagsted J., Jensen S.K., Karlsson A.H. and Henckel P. (2003). Ascorbic acid, a-tocopherol and oregano supplements reduce stress-induced deterioration of chicken meat quality. Poult. Sci. 82, 1343-1351.
Zednik J., Marecek E., Zidova M., Valdhauser A., Urbanek J., Verner V., Huskova J., Kubenova H. and Matycka L. (1994). Effect of herbal preparation Galog and HB Forte on milk production of dairy cows. Int. J. Indigen. Med. 10, 11-20.
Zhang W. and Wang S.Y. (2001). Antioxidant activity and phenoliccompounds in selected herbs. J. Agric. Food Chem. 49, 5165-5170.
Zhou B., Wu L.M., Yang L. and Liu Z.L. (2005). Evidence for tocopherol regeneration reaction of green tea polyphenols in SDS micelles. Free Radical Biol. Med. 38, 78-84.
Volume 5, Issue 3 - Serial Number 3
September 2015
Pages 497-516
  • Receive Date: 25 July 2014
  • Revise Date: 17 August 2014
  • Accept Date: 31 August 2014
  • First Publish Date: 01 September 2015