Increased Fecal Ethanol and Methanol Concentration in Dairy Heifers after Grazing

Document Type : Short Communication

Authors

School of Veterinary Medicine, University of Rakuno Gakuen, Ebetsu, Japan

Abstract

To clarify fermentative alterations in the large intestine (hindgut) during grazing, fecal alcohol and volatile fatty acids (VFAs) concentrations were evaluated in 30 dairy heifers. The heifers were kept in pasture growing mixed grass herbage from spring (mid May) until October, and their rectal feces were collected periodically. Concentrations of ethanol, methanol and isopropanol were increased in runny feces at early stage of grazing, but gradually decreased thereafter, despite the fact that ethanol remained at a high level until early October. Fecal VFA concentration was barely influenced at early grazing stage; however, it showed marked decrease thereafter. Hindgut exposure of increased nutrients which escaped upper tract digestion might promote active alcoholic fermentation in the colon of the heifers, particularly during early grazing period when runny defecation happens frequently.

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Ekins B.R., Rollins D.E., Duffy D.P. and Gregory M.C. (1985). Standardized treatment of severe methanol poisoning with ethanol and hemodialysis. West. J. Med. 142, 337-340.
Freund J.E. (1988). Modern Elementary Statistics, 7th Ed. Prentice-Hall, New Jersey. Pp. 490-493 and 499-502. Hoover W.H. (1978). Digestion and absorption in the hindgut of ruminants. J. Anim. Sci. 46, 1789-1799.
Krebs H.A. and Perkins J.R. (1970). The physiological role of liver alcohol dehydrogenase. Biochem. J. 118, 635-644.
Larson I.L., Owen F.G., Albright J.L., Appleman R.D., Lamb R.C. and Muller L.D. (1977). Guidelines toward more uniformity in measuring and reporting calf experimental data. J. Dairy Sci. 60, 989-991.
Macfarlane S. and Macfarlane G.T. (2003). Regulation of short-chain fatty acid production. Proc. Nutr. Soc. 62, 67-72.
Majchrowicz E. and Mendelson J.H. (1971). Blood methanol concentrations during experimentally induced ethanol intoxication in alcoholics. J. Pharmacol. Exp. Ther. 179, 293-300.
Miller W.J. (1979). Dairy Cattle Feeding and Nutrition, Academic Press, New York. Pp. 358.
Ørskov E.R. and Ryle M. (1990). Energy Nutrition in Ruminants, Elsevier Science Publisher, Essex. Pp. 43-51.
Osbourn D.F. (1989). The Feeding Value of Grass and Grass Products, in Grass, Its Production and Utilization, 2nd Ed. W. Holmes, ed. Blackwell, London.Pp. 89-129.
Sato H. (2010). Fecal acetone and isopropanol levels of wild sika deer (Cervus nippon yesoensis) in spring and winter. Grassl. Sci. 56, 56-58.
Sato H. and Nakajima J. (2005). Fecal ammonia, urea, volatile fatty acid and lactate levels in dairy cows and their pathophysiological significance during diarrhea. Anim. Sci. J. 76, 595-599.
Sato H. and Shiogama Y. (2010). Acetone and isopropanol in ruminal fluid and feces of lactating dairy cows. J. Vet. Med. Sci. 72, 297-300.
Topping D.L. and Clifton P.M. (2001). Short-chain fatty acids and human colonic function: Roles of resistant starch and nonstarch polysaccharides. Physiol. Rev. 81,1031-1064.
Van Soest P.J., Robertson J.B. and Lewis B.A. (1991). Methods for dietary fiber, neutral detergent fiber, and nonstarch polysaccharides in relation to animal nutrition. J. Dairy Sci. 74, 3583-3597.
Williams B.A., Verstegen M.W.A. and Tamminga S. (2001). Fermentation in the large intestine of single- stomached animals and its relationship to animal health. Nutr. Res. Rev. 14, 207-227.