Therapeutic Evaluation of Mineral Preparation for the Amelioration of Anaemia in Goats of Arid Zone of Rajasthan

Document Type: Research Articles


1 Department of Clinical Veterinary Medicine, Ethics and Jurisprudence College of Veterinary and Animal Science, Rajasthan University of Veterinary and Animal Science, Bikaner Rajasthan, 334001, India

2 Department of Animal Nutrition, College of Veterinary and Animal Science, Rajasthan University of Veterinary and Ani- mal Science, Bikaner Rajasthan, 334001, India


An experiment was conducted on eight weak and anaemic goats revealed pale conjunctivae, increased heart rate, rough hair coat, dullness and depression. The haematology showed significantly decreased haemoglobin (7.37±0.16 g %), packed cell volume (PCV)(23.37±0.56%),total erythrocyte count (TEC)(8.12±0.18 million/cumm), mean corpuscular haemoglobin (MCH) (9.10±0.30 pg) and mean corpuscular volume (MCV) (28.82±0.80 fl) in anaemic goats as compared to healthy goats. In anaemic goats, the serum level of total protein, albumin,albumin-globulin (A-G) ratio and blood glucose levels were significantly reduced. Biochemical analysis revealed decreased serum copper, cobalt and iron levels in anaemic goats. After haemato-biochemical analysis, anaemic goats were given a mineral preparation i.e., tablets COFECU plus at one tablet daily orally for 30 days. The anaemic goats gradually recovered by alleviating the anaemic syndrome in 30 days of treatment. The haemoglobin (Hb), packed cell volume (PCV), total erythrocyte count (TEC), mean corpuscular haemoglobin (MCH)and mean corpuscular volume (MCV)parameters showed improvement after treatment but are not comparable with the values recorded for healthy control goats indicating some more duration for better recovery. No significant variations in neutrophils, lymphocytes, monocytes, eosinophils and basophilsvalues were observed in anaemic goats before and after treatment. The biochemical parameters revealed decrease in total serum protein, albumin,albumin-globulin (A-G) ratio and glucose values in goats suffering from anaemia, which recovered satisfactorily as a result of treatment regimens given for 30 days. A significant improvement in serum copper, cobalt and iron levels were observed after treatment of 30 days but could not reach to the level of control. It can be concluded that tablet COFECU plus is quite effective with slow recovery rate in treating the nutritional anaemia in goats and suggest an increase in treatment period.


Benjamin M.M. (1977). Outline of Veterinary Clinical Pathology. 3rd Ed., Kalyani Publishers, New Delhi.
Bhikane A.U., Ambore B.N., Yadav G.U. and Bharkad G.P. (2006). Efficacy of organic iron in the treatment of anaemia in goats. Indian Vet. J. 83, 320-322.
Chaudhary P.S., Chauhan H.V.S., Deshmukh V.V. and Moliya D.C. (2008). Treatment of anaemia in cow calves by feritas bolus. Intas Polivet. 9(1), 43-45.
Dhaliwal M.K. (1996). Clinical studies on anaemia in crossbred cows with reference to Copper (Cu), Cobalt (Co) and Iron (Fe) deficiency. M S. Thesis. Rajasthan Agricultural University, Bikaner.
Fraser C.M., Bergeson J.A., Mays A. and Aillo E.S. (1991). The Merck Veterinary Manual, 7th Ed., Merck and Co., USA.
JainN.C.(1986). Schalm’s Veterinary Haematology, 4th Ed., Lea and Febiger, Philaldelphia.
Katoch A. and Mandial R.K. (2003). Clinico haematological, biochemical and therapeutic studies on anaemia in cattle. Indian J. Vet. Med. 23(2), 75-78.
Kumar H. (2007). Clinico-therapeutic studies on anaemia in camels (Camelus dromedarius) cows with reference to copper, cobalt and Iron. M S. Thesis. Rajasthan Agricultural University, Bikaner.
Pinta M. (1979). Modern Methods for Trace Element Analysis. Ann. Arbor Science Publishers, Inc. Michingen (USA).
Rajguru D.N., Pawar L.S., Mohd S. and Joshi A. (2002). A haemato-biochemical alterations and therapeutic management of endoparasite induced caprine anaemia.Indian Vet. J. 79, 973-975.
Rajkhowa S. and Hazarika G.C. (2002). Effect of age, sex and season on the prevalence of anaemia in goats. Indian J. Vet. Med. 22(1), 45-46.
Samanta A.K., Sarkar S., Bose S., Duttagupta R., Senapati P.K. and Bhowmik M.K. (1995). Influence of macro and micro minerals on anaemia related to production and reproduction of grazing cattle. Indian Vet. J. 75(10), 1031-1034.
Sarkar S., Bhowmik M.K., Basak D.N., Pan S. and Mishra S.K. (1992). Prevalence of anaemia in goats of alluvial zone of West Bengal. Indian J. Anim. Sci. 62(2), 100-102.
Sarkar S. and Mishra S.K. (1991). Haematological changes in experimentally induced nutritional anaemia in goats and its therapy. Indian Vet. J. 68(8), 769-774.
Sarkar S., Mishra S.K. and Das S.K. (1990). Soil, plant and animal relationship in respect of micronutrient in anaemic Black Bengal goats (Capra hircus). Indian J. Anim. Health. 29, 59-64.
Sarkar S., Bhowmik M.K. and Biswas S. (1995). Micromineral deficiency anaemia in grazing goats with a therapy note. Indian J. Vet. Pathol. 19(2), 108­-111.
Sarkar S., Samanta T.K., Biswas U. and Bhowmik M.K. (1996). A note on anaemia and anoestrous in cattle and therapy with COFECU Plus. Indian J. Anim. Health. 35(1), 105-106.
Schalm O.W., Jain N.C. and Carrol E.J. (1975). Veterinary Haematology. 3rd Ed., Lea and Febiger, Philadelphia.
Smith M.C. and Sherman D.M. (1994). Goat Medicine. Ist Ed., Lea and Febiger, Philadelphia.
Snedecor G.W. and Cochran W.H. (1994). Statistical Methods. Oxford IBH Publishing Co., Calcutta.
Tietz N.W. (1990). Clinical Laboratory Tests. 2nd Ed. W.B.Saunders Co. Philadelphia.
Tufani N.A. and Haque S. (2007). Comparative efficacy of different mineral preparation in crossbred calves. Indian J. Vet. Med. 27(2), 135-137.
Wadhwa D.R, Prasad B. and Rao V.N. (2001). Haemato-biochemical changes in enzootic bovine haematuria. Indian J. Vet. Med.21,21-24.
Welchman D., De B., Whelehan O.P. and Webster A.J.F. (1988). Haematology of veal calves reared on different husbandry systems and the assessment of iron deficiency. Vet. Rec. 123(20), 505-510.